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Table 4 Diagnostic performance of livin/BIRC7 expression, catalase, and malondialdehyde (MDA) for prediction of endometrial hyperplasia

From: Livin/BIRC7 gene expression as a possible diagnostic biomarker for endometrial hyperplasia and carcinoma

 

Livin/BIRC7 expression

Catalase

MDA

Cutoff

> 0.30

> 0.14

> 4.12

AUC

0.950

0.530

0.970

Sensitivity %

96.7%

70.0%

100%

Specificity %

90.0%

36.7%

83.3%

Accuracy

86%

7%

83%

PPV %

90.6%

52.5%

85.7%

NPV %

96.4%

55.0%

100.0%

95% CI

0.87-0.99

0.39-0.66

0.89-0.99

p value

< 0.001

0.66

< 0.001

  1. AUC: area under the curve, PPV: positive predictive value, NPV: negative predictive value, CI: confidence interval