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Table 3 The affinity for the mutant and wild type N proteins for the M protein at 25 and 35 °C. As it can be seen, the mutant appears to display more temperature sensitivity than the wild type, with its affinity for the M protein decreasing over this range

From: Analysing the impact of the two most common SARS-CoV-2 nucleocapsid protein variants on interactions with membrane protein in silico

Protein Temperature (°C) Affinity for M protein (M)
Mutant isolate N protein 25 5.30E−11
35 1.10E−10
Wuhan virus N protein 25 1.30E−09
35 2.50E−09