Table 3 The affinity for the mutant and wild type N proteins for the M protein at 25 and 35 °C. As it can be seen, the mutant appears to display more temperature sensitivity than the wild type, with its affinity for the M protein decreasing over this range

From: Analysing the impact of the two most common SARS-CoV-2 nucleocapsid protein variants on interactions with membrane protein in silico