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Table 5 Relation of TLR4 genotypes versus demographic, clinical, and outcome data in vitiligo group 1 (below 18 years) patients

From: TLR4 gene polymorphisms in Egyptian vitiligo patients: insights into emerging association with clinical activity, family history, and response to therapy

SNPs

rs1927914

rs1927911

rs11536858

CC

N/%

CT

N/%

TT

N/%

CC

N/%

CT

N/%

TT

N/%

AA

N/%

AG

N/%

GG

N/%

Sex

M/F

0.20/0.03

0.20/0.15

0.60/0.81

0.10/0.15

0.80/0.69

0.10/0.15

0.20/0.24

0.70/0.57

0.10/0.18

p

0.13

0.66

0.15

1.0

0.53

1.0

1.0

0.48

1.0

Course

Regressive/Progressive

0.00/0.13

0.00/0.13

1.00/0.73

0.00/0.17

1.00/0.61

0.00/0.22

0.00/0.22

1.00/0.70

0.00/0.09

p

1.0

1.0

1.0

1.0

1.0

1.0

1.0

1.0

1.0

Psychiatric trauma

+/−

0.33/0.09

0.00/0.14

0.67/0.76

0.00/0.19

0.67/0.62

0.33/0.19

0.00/0.24

1.00/0.67

0.00/0.09

p

1.0

1.0

1.0

1.0

1.0

0.52

1.0

0.53

1.0

Alopecia

+/−

1.00/0.09

0.00/0.13

0.00/0.78

0.00/0.17

1.00/0.60

0.00/0.22

0.00/0.22

1.00/0.69

0.00/0.09

p

0.13

1.0

0.25

1.0

1.0

1.0

1.0

1.0

1.0

FH of vitiligo

+/−

0.25/0.10

0.25/0.10

0.50/0.80

0.25/0.15

0.50/0.65

0.25/0.20

0.00/0.25

1.00/0.65

0.00/0.10

p

0.44

0.44

0.25

0.54

0.62

1.0

0.54

0.28

1.0

FHAIDs

+/−

0.00/0.14

0.50/0.09

0.50/0.77

0.50/0.14

0.00/0.68

0.50/0.18

0.00/0.23

1.00/0.68

0.00/0.09

p

1.0

0.24

0.45

0.31

0.13

0.38

1.0

1.0

1.0

Remission

+/−

0.29/0.06

0.14/0.12

0.57/0.85

0.43/0.06

0.43/0.71

0.14/0.24

0.29/0.18

0.57/0.77

0.14/0.06

p

0.19

1.0

0.31

0.06

0.36

1.0

0.61

0.37

0.51

Type

Segmental/Nonsegmental

0.00/0.15

0.00/0.15

0.00/0.30

0.00/0.20

0.75/0.60

0.20/0.20

0.00/0.25

1.00/0.65

0.00/0.10

p

1.0

1.0

0.54

1.0

1.0

1.0

0.54

0.28

1.0

  1. M/F male/female, R/P regressive/progressive, Seg/Nonseg segmental/nonsegmental, FH family history, FHAIDs family history of auto-immune diseases, p value significant if < 0.05
  2. Fischer Exact test: no significant associations were detected