Table 4 Distribution of TLR4 alleles and genotypes vitiligo patients and healthy controls (group 2: above 18 years)
TLR4 polymorphisms | Case (N—76) N (%) | Control (N = 81) N (%) | OR (95% CI) | p/pc |
|---|---|---|---|---|
rs1927914 (C/T) | ||||
CC | 12 (15.8) | 7 (8.6) | 1.98 (0.74–5.34) | 0.17/NS |
CT | 8 (10.5) | 22 (27.2) | 0.32 (0.13–0.76) | 0.01/0.03 |
TT | 56 (73.7) | 52 (64.2) | 0.64 (0.32–1.27) | 0.20/NS |
C | 32 (21.0) | 36 (22.2) | 0.93 (0.55–1.60) | 0.80/NS |
T | 120 (79.0) | 126 (77.8) | 1.07 (0.62–1.83) | 0.80/NS |
rs1927911 (C/T) | ||||
CC | 13 (17.1) | 26 (32.1) | 0.44 (0.21–0.93) | 0.03/NS |
CT | 50 (65.8) | 42 (51.9) | 1.79 (0.94–3.40) | 0.08/NS |
TT | 13 (17.1) | 13 (16.0) | 0.93 (0.39–2.15) | 0.44/NS |
C | 76 (50.0) | 94 (58.0) | 0.72 (0.46–1.13) | 0.15/NS |
T | 76 (50.0) | 68 (42.0) | 1.38 (0.88–2.16) | 0.15/NS |
rs11536858 (A/G) | ||||
AA | 19 (25.0) | 20 (24.7) | 1.02 (0.49–2.09) | 0.96/NS |
AG | 45 (59.2) | 49 (60.5) | 0.94 (0.50–1.80) | 0.87/NS |
GG | 12 (15.8) | 12 (14.8) | 0.93 (0.39–2.21) | 0.87/NS |
A | 83 (54.6) | 89 (54.9) | 0.99 (0.63–1.54) | 0.95/NS |
G | 69 (45.4) | 73 (45.1) | 1.01 (0.64–1.58) | 0.95/NS |