Skip to main content
Journal of Genetic Engineering and Biotechnology

Table 4 Effect of Crateva adansonii leaf extracts and its Lupeol containing LF on acetic acid-induced writhing in mice

From: Analgesic and anti-inflammatory potential of Lupeol isolated from Indian traditional medicinal plant Crateva adansonii screened through in vivo and in silico approaches

Groups

Drug treatment

Writhing count for 20 min

Percentage of analgesic activity

I

Control 0.1%CMC

65.45 ± 2.50

–

II

Indomethacin 20 mg/kg

19.60 ± 0.95***

70.05%

III

ME 200 mg/kg

48.33 ± 2.22*

26.16%

IV

ME 400 mg/kg

38.671.75**

40.92%

V

CE 200 mg/kg

36.76 ± 2.22**

43.83%

VI

CE 400 mg/kg

25.35 ± 1.55***

61.26%

VII

LF 100 mg/kg

20.26 ± 0.98***

69.05%

  1. The data are presented as mean ± SEM n = 6. *p < 0.05, **p < 0.01, and ***p < 0.001 vs. control. Data were analyzed by using one-way ANOVA followed by Dunnett’s “t” test using the software Graph Pad
  2. ME Methanolic extract of C. adansonii leaf, CE Chloroform extract of C. adansonii leaf, LF Lupeol fraction
Back to article page