Variables | AUC | Cut-off | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | Efficiency (%) |
---|---|---|---|---|---|---|---|
Healthy vs CRC | |||||||
CEA ng/ml | 0.37 | 2.8 | 79 | 10 | 68 | 17 | 59 |
CA 19.9 μ/ml | 0.41 | 23.4 | 77 | 10 | 67 | 15 | 57 |
PLR | 0.73 | 4.9 | 47 | 65 | 76 | 34 | 52 |
SCF ng/ml | 0.80 | 539 | 58 | 90 | 93 | 47% | 63 |
LRG1 μg/ml | 0.87 | 60 | 52 | 90 | 93 | 44 | 68 |
SCF-LRG1 | 0.9 | 3.6 | 85 | 80 | 91 | 70 | 84 |
CRC vs Benign | |||||||
CEA ng/ml | 0.44 | 2.8 | 79 | 20 | 70 | 29 | 62 |
CA 19.9 μ/ml | 0.50 | 23.4 | 77 | 30 | 73 | 35 | 63 |
PLR | 0.48 | 4.9 | 45 | 60 | 72 | 32 | 49 |
SCF ng/ml | 0.72 | 539 | 58 | 70 | 82 | 41 | 61 |
LRG1 μg/ml | 0.84 | 60 | 54 | 95 | 96 | 46 | 66 |
SCF-LRG1 | 0.84 | 3.6 | 79 | 70 | 86 | 58 | 77 |
Treated CRC vs non-treated CRC | |||||||
CEA ng/ml | 0.59 | 2.8 | 82 | 23 | 47 | 60 | 50 |
CA 19.9 μ/ml | 0.64 | 23.4 | 82 | 27 | 49 | 64 | 52 |
PLR | 0.76 | 4.55 | 71 | 69 | 65 | 75 | 70 |
SCF ng/ml | 0.68 | 539 | 73 | 54 | 57 | 70 | 63 |
LRG1 μg/ml | 0.82 | 61.5 | 82 | 73 | 72 | 83 | 73 |
SCF-LRG1 | 0.84 | 3.6 | 77 | 70 | 68 | 78 | 77 |