Journal of Genetic Engineering and Biotechnology

Table 6 Predicted amino acid substitution effects in tested genes

From: Assessment of correlation between asthenozoospermia and mitochondrial DNA mutations in Egyptian infertile men

Variant	PROVEAN score	Prediction (cutoff = − 2.5)
ND1
M15T	− 5.188	Deleterious
L156P	− 3.248	Deleterious
D232N	1.312	Neutral
L273P	− 4.407	Deleterious
Y288H	− 0.759	Neutral
ND2
*M33V*	*− 0.092*	*Neutral*
*T217I*	*2.952*	*Neutral*
L221I	− 1.829	Neutral
ATPase 6
T3A	*− 0.830*	Neutral
T56A	*− 4.013*	Deleterious

Italic amino acid indicates a mutual change in the normozoospermic and asthenozoospermic groups. Bold amino acid indicates a mutual change in the asthenozoospermic group only

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