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Table 6 Predicted amino acid substitution effects in tested genes

From: Assessment of correlation between asthenozoospermia and mitochondrial DNA mutations in Egyptian infertile men

Variant PROVEAN score Prediction (cutoff = − 2.5)
ND1
M15T − 5.188 Deleterious
L156P − 3.248 Deleterious
D232N 1.312 Neutral
L273P − 4.407 Deleterious
 Y288H − 0.759 Neutral
ND2
M33V − 0.092 Neutral
T217I 2.952 Neutral
L221I − 1.829 Neutral
ATPase 6
T3A − 0.830 Neutral
T56A − 4.013 Deleterious
  1. Italic amino acid indicates a mutual change in the normozoospermic and asthenozoospermic groups. Bold amino acid indicates a mutual change in the asthenozoospermic group only
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