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Table 5 Association between rs12503843 and clinicopathological markers

From: Heparanase (HPSE) gene polymorphism (rs12503843) contributes as a risk factor for hepatocellular carcinoma (HCC): a pilot study among Egyptian patients

Variables

rs12503843

P

TT (n = 4)

CT (n = 29)

CC (n = 37)

No.

No.

No.

No.

No.

No.

ALT

 Mean ± SD

45.0–8.29

55.86 ± 43.14

43.30 ± 25.47

0.267

AST

 Mean ± SD

70.50 ± 24.72

67.21 ± 67.21

51.59 ± 21.52

0.62

AFP

 Mean ± SD

191.20 ± 336.35

1015.56 ± 2441.89

1401.52 ± 2899.74

0.599

Child-Pugh score

 A

1

25.0

20

69.0

21

56.8

0.313

 B

3

75.0

9

31.0

14

37.8

 C

0

0.0

0

0.0

2

5.4

Number of hepatic focal lesion

 1

3

75.0

19

65.5

24

64.9

MCP = 0.827

 2

1

25.0

4

13.8

9

24.3

 3

0

0.0

2

6.9

2

5.4

 > 3

0

0.0

4

13.8

2

5.4

Size (cm)

 Mean ± SD

6.38 ± 4.46

4.71 ± 3.22

5.22 ± 2.97

0.325

HCV

 Negative

0

0.0

3

10.4

4

10.8

MCP = 1.0

 Positive

4

100.0

26

89.7

33

89.2

  1. MC Monte Carlo