Green synthesis of silver and iron nanoparticles of isolated proanthocyanidin: its characterization, antioxidant, antimicrobial, and cytotoxic activities against COLO320DM and HT29

Journal of Genetic Engineering and Biotechnology

Table 2 Results of cytotoxicity of PAC, PACAgNPs, and PACFeNP by MTT and SRB assay using COLO320DM and HT29 cell lines

Compound	Mean OD	Percent inhibition	Percent viability
MTT assay against HT29 (control—0.321)
Proanthocynidin plain	0.161	49.53 ± 1.54	47.13 ± 3.32
Proanthocynidin AgNP	0.117	63.34 ± 1.64	36.65 ± 1.64
Proanthocynidin FeNP	0.129	59.39 ± 1.84	40.60 ± 1.84
MTT assay against COLO320DM (control—0.384)
Proanthocynidin plain	0.146	61.49 ± 1.66	35.51 ± 1.66
Proanthocynidin AgNP	0.137	64.27 ± 1.63	35.72 ± 1.63
Proanthocynidin FeNP	0.142	63.17 ± 1.63	36.49 ± 2.07
SRB assay against HT29 (control—0.292)
Proanthocynidin plain	0.204	30.71 ± 1.88	69.29 ± 1.88
Proanthocynidin AgNP	0.090	69.21 ± 1.86	30.78 ± 1.86
Proanthocynidin FeNP	0.115	60.57 ± 2.20	39.43 ± 2.20
Proanthocynidin plain	0.204	30.71 ± 1.88	69.29 ± 1.88
SRB assay against COLO320DM (control—0.252)
Proanthocynidin plain	0.209	17.11 ± 1.72	82.89 ± 1.72
Proanthocynidin AgNP	0.073	71.6 ± 1.97	28.4 ± 1.97
Proanthocynidin FeNP	0.141	44.60 ± 2.18	55.39 ± 2.18