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Table 2 Results of cytotoxicity of PAC, PACAgNPs, and PACFeNP by MTT and SRB assay using COLO320DM and HT29 cell lines

From: Green synthesis of silver and iron nanoparticles of isolated proanthocyanidin: its characterization, antioxidant, antimicrobial, and cytotoxic activities against COLO320DM and HT29

Compound Mean OD Percent inhibition Percent viability
MTT assay against HT29 (control—0.321)
 Proanthocynidin plain 0.161 49.53 ± 1.54 47.13 ± 3.32
 Proanthocynidin AgNP 0.117 63.34 ± 1.64 36.65 ± 1.64
 Proanthocynidin FeNP 0.129 59.39 ± 1.84 40.60 ± 1.84
MTT assay against COLO320DM (control—0.384)
 Proanthocynidin plain 0.146 61.49 ± 1.66 35.51 ± 1.66
 Proanthocynidin AgNP 0.137 64.27 ± 1.63 35.72 ± 1.63
 Proanthocynidin FeNP 0.142 63.17 ± 1.63 36.49 ± 2.07
SRB assay against HT29 (control—0.292)
 Proanthocynidin plain 0.204 30.71 ± 1.88 69.29 ± 1.88
 Proanthocynidin AgNP 0.090 69.21 ± 1.86 30.78 ± 1.86
 Proanthocynidin FeNP 0.115 60.57 ± 2.20 39.43 ± 2.20
 Proanthocynidin plain 0.204 30.71 ± 1.88 69.29 ± 1.88
SRB assay against COLO320DM (control—0.252)
 Proanthocynidin plain 0.209 17.11 ± 1.72 82.89 ± 1.72
 Proanthocynidin AgNP 0.073 71.6 ± 1.97 28.4 ± 1.97
 Proanthocynidin FeNP 0.141 44.60 ± 2.18 55.39 ± 2.18
  1. Values are expressed in triplicate mean SD