Skip to main content
Journal of Genetic Engineering and Biotechnology

Table 2 Antitumor activity of the biosynthesized AgNPs

From: Biosynthesis and characterization of silver nanoparticles induced by fungal proteins and its application in different biological activities

Cell line

Antitumor activity

IC50 (μg/ml)

IC90 (μg/ml)

Inhibition (%) at 54 ppm

BJ1 (normal skin fibroblast)

–

–

15.6

HCT116 (colon cell line)

31.1

52.3

84.6

A549 (lung carcinoma cell line)

45.4

72.8

60.8

MCF7 (human Caucasian breast adenocarcinoma)

40.9

65.7

68.9

PC3 (prostate cell line)

33.5

60.7

69.5

  1. IC50 lethal concentration of the sample which causes the death of 50% of cells in 48 h, IC90 lethal concentration of the sample which causes the death of 90% of cells in 48 h
Back to article page