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Table 2 Genotype and percentage frequency of TNF-alpha polymorphism (rs1800629)-308 G/A and their Hardy–Weinberg equilibrium (HWE) of the studied groups

From: Estimating the role of single-nucleotide polymorphism (rs1800629)-308 G/A of TNF-alpha gene as genetic marker associated with angina pectoris in a sample of Iraqi patients

Subjects group

Genotypes

HWE analysis of TNF-α genotypes

 

GG

GA

AA

p-value

χ2

Stable angina (n = 100)

Observed (N %)

28 (28%)

53 (53%)

19 (19%)

P > 0.05 (NS)

0.47

Expected (N %)

29.70 (29.70%)

49.59 (49.59%)

20.70 (20.70%)

Unstable angina (n = 100)

Observed (N %)

30 (30%)

33 (33%)

37 37(%)

P ≤ 0.01 (S)

11.34

Deviation

Expected (N %)

21.62 (21.62%)

49.75 (49.75%)

28.62 (28.62%)

Control (n = 100)

Observed (N %)

61 (61%)

28 (28%)

11 (11%)

P ≤ 0.05 (S)

6.41

Deviation

Expected (N %)

56.25 (56.25%)

37.5 (37.5%)

6.25 (6.25%)

  1. S, significant; NS, non-significant. χ2, chi-square distribution