Journal of Genetic Engineering and Biotechnology

Table 2 Drug-likeness properties of the top-two ligand

From: Bioinsecticidal activity of actinomycete secondary metabolites against the acetylcholinesterase of the legume’s insect pest Acyrthosiphon pisum: a computational study

	MW g/mol	logP	Log S	HBA	HBD	TPSA (Å²)	AMR	nRB	Lipinski	Ghose	Veber	Egan	Muegge
Diazepinomicin	462.58	5.42	−6.73	4	4	98.48	142.09	8	Yes	No	Yes	No	Yes
Hygromycin	511.48	−1.47	−1.54	12	7	204.47	118.27	7	No	No	No	No	No

HBA Num. H-bond acceptors, HBD Num. H-bond donors, nRB Num. rotatable bonds, AMR atom molar refractivity

Back to article page