Fig. 1From: Studying the characteristics of nanobody CDR regions based on sequence analysis in combination with 3D structuresCDRs of Nbs. A Representative Nb sequences with CDR1, CDR2, and CDR3 separated by conserved frameworks; residue positions were numbered by the widely used Martin scheme [1]. The Martin numbering scheme can accurately define the position of residues in the Nb sequences, which can then be used to locate the CDR automatically and conveniently. Positions with different residue alignment were colored in grey. These Nbs interacted with internalin B (gi: 1446209568, pdb: 6DBE), KRT19 (gi: 395406684), and melanoma-associated antigen B1 (gi: 1631826412, pdb: 6R7T), respectively. B CDR1, CDR2, and CDR3 loops in a crystallized structureBack to article page