Table 3 Prediction of changes on the protein stability
From: An in silico analysis of rpoB mutations to affect Chlamydia trachomatis sensitivity to rifamycin
SNP | I-Mutant3 | MUpro | ||
|---|---|---|---|---|
ΔΔG | Prediction | ΔΔG | Prediction | |
V136F | − 1.37 | DECREASE | − 0.68 | Decrease |
Q458K | − 0.56 | DECREASE | − 1.62 | Decrease |
V466A | − 1.51 | DECREASE | − 0.93 | Decrease |
A467T | − 0.84 | DECREASE | − 0.9 | Decrease |
H471N | − 0.62 | DECREASE | − 0.82 | Decrease |
H471Y | 0.27 | INCREASE | − 0.36 | Decrease |
H471L | 0.52 | INCREASE | − 0.05 | Decrease |
I517M | − 1.68 | DECREASE | − 0.68 | Decrease |