Table 5 SPR kinetic values obtained for FcγRIIIa V158 (A and B) and F158 (C and D) receptors for the test anti-CD20 antibody and control antibody
Receptor | Samples | KD (nM) | ka (1/Ms) | kd (1/s) |
|---|---|---|---|---|
FcγRIIIa V 158 | Control antibody (RS-03-25) | 75.4 | 8.028E + 04 | 0.006054 |
Test antibody (P2-CRD-1508) | 56.4 | 1.234E + 05 | 0.006963 | |
FcγRIIIa F 158 | Control antibody (RS-03-25) | 143.3 | 8.387E + 04 | 0.01202 |
Test antibody (P2-CRD-1508) | 136.0 | 1.629E + 05 | 0.02214 |