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Table 1 Details of process parameters of the 5000 mL production bioreactor

From: Enhancement of effector functions of anti-CD20 monoclonal antibody by increased afucosylation in CHO cell line through cell culture medium optimization

Parameters

Set value

Duration

Temperature (°C)

37

Day 0 to 5

34

Day 5 to 7

32

Day 7 to 10

30

Day 10 to 11

DO (%)

30

Day 0 to 11

pH

7.2

Day 0 to 11