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Journal of Genetic Engineering and Biotechnology
Fig. 1 | Journal of Genetic Engineering and Biotechnology

Fig. 1

From: Enhancement of effector functions of anti-CD20 monoclonal antibody by increased afucosylation in CHO cell line through cell culture medium optimization

Fig. 1

Diagrams showing the expression vectors with the cloned light (A) and heavy chain (B) sequences. pMOZ-G62 carry neomycin resistance (NEO) gene as a dominant selectable marker. pMOZ-G82 vector contains a copy of the mouse dihydrofolate reductase (DHFR) gene under control of the SV40 early promoter. DHFR confers methotrexate resistance in Chinese hamster ovary cells (CHO) which lack dihydrofolate reductase. Both vectors carry mouse cytomegalovirus (MCMV) promotor elements and rabbit beta globin polyadenylation (rBGp(A)) signals

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