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Table 2 Biochemical characteristics of subjects in the different studied groups

From: Association study of HIF-1α rs11549465 and VEGF rs3025039 genetic variants with diabetic retinopathy in Egyptian patients: crosslinks with angiogenic, inflammatory, and anti-inflammatory markers

 

Control (n = 72)

DWR (n = 72)

NPDR (n = 72)

PDR (n = 72)

FPG (mg%)

83.00 (18.00)

187.00 (83.50)

283.50 (27.25)

307.00 (50.00)

P value

 

< 0.0001a

< 0.0001a, b

< 0.0001a, b/0.034c

HbA1C (%)

4.80 (0.67)

7.14 (1.18)

7.89 (1.22)

9.74 (2.02)

P value

 

< 0.0001a

< 0.0001a/0.677b

< 0.0001a, b/< 0.0001c

TG (mg%)

100.00 (70.75)

189.00 (40.75)

162.00 (45.25)

178.00 (49.50)

P value

 

< 0.0001a

< 0.0001a/0.001b

< 0.0001a/0.242b/0.516c

TC mg%)

187.00 (79.50)

226.00 (74.00)

220.50 (62.75)

270.00 (90.75)

P value

 

< 0.0001a

0.105a/0.389b

< 0.0001a/0.151b/< 0.0001c

HDL-C (mg%)

93.50 (29.50)

79.50 (37.25)

68.50 (38.75)

65.50 (53.75)

P value

 

0.468a

< 0.0001a/0.008b

< 0.0001a/0.001b/1.000c

LDL-C (mg%)

76.50 (49.90)

115.80 (54.15)

122.80 (78.35)

155.40 (116.60)

P value

 

0.003a

< 0.0001a/1.000b

< 0.0001a/0.005b/0.024c

VLDL-C (mg%)

20.00 (14.15)

37.80 (8.15)

32.40 (9.05)

35.60 (9.90)

P value

 

< 0.0001a

< 0.0001a/0.001b

< 0.0001a/0.242b/0.516c

  1. Data are expressed as median (interquartile range)
  2. DWR diabetes without retinopathy, NPDR non-proliferative retinopathy, PDR proliferative diabetic retinopathy, FPG fasting plasma glucose, HbA1c glycated hemoglobin, TG triacylglycerol, TC total cholesterol, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, VLDL-C very-low-density lipoprotein cholesterol
  3. aSignificance versus control group
  4. bSignificance versus DWR group
  5. cSignificance versus NPDR group
  6. Significance had been adjusted by Bonferroni correction for multiple tests
  7. The mean difference is significant at p < 0.05