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Table 5 Multiple linear regression analysis for the association of systemic oxidative stress markers with the IOP average

From: Impact of rs11024102 PLEKHA7, rs3753841 COL11A1 single nucleotide polymorphisms, and serum levels of oxidative stress markers on the risk of primary angle-closure glaucoma in Egyptians

Dependent variable

Predictors

R

r2

F

P value*

β

t

P value

VIF

IOP averagea

MDA (nmol/ml)

0.40

0.13

4.49

0.002

0.29

2.86

0.005

1.17

AOPP (mmol/L)

    

−0.07

−0.66

0.510

1.18

PC (nmol/ml)

    

0.15

1.53

0.129

1.08

IMA (ABSU)

    

0.18

1.84

0.07

1.09

IOP averageb

MDA (nmol/ml)

0.50

0.25

4.83

0.002

0.34

2.80

0.007

1.11

AOPP (mmol/L)

    

−0.06

−0.51

0.612

1.08

PC (nmol/ml)

    

0.25

2.05

0.045

1.11

IMA (ABSU)

    

0.21

1.78

0.08

1.04

  1. IOP intraocular pressure, β standardized coefficient, VIF variance inflation factor, MDA malondialdehyde, AOPP advanced oxidation protein products, IMA ischemia-modified albumin, ABSU absorbance units
  2. *P value obtained from ANOVA table
  3. aAll subjects (n=35 for control subjects, n=64 for PACG patients), bControl and PACG subjects after excluding subjects with DM, hypertension, CVD, and smoking (n= 26 for the control group and 36 for PACG patients)
  4. P < 0.05 was considered significant