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Table 4 Association between markers of systemic oxidative stress and PACG risk using binary logistic regression

From: Impact of rs11024102 PLEKHA7, rs3753841 COL11A1 single nucleotide polymorphisms, and serum levels of oxidative stress markers on the risk of primary angle-closure glaucoma in Egyptians

 

PACG vs. control

#Adjusted OR (95% CI)

P value

MDA (nmol/ml)a

1.70 (1.35–2.14)

<0.0001

MDA (nmol/ml)b

2.50 (1.56–4.01)

<0.0001

AOPP (mmol/L)a

1.03 (1.01–1.05)

0.001

AOPP (mmol/L)b

1.04 (1.01–1.07)

0.005

PC (nmol/ml)a

1.43 (1.15–1.78)

0.001

PC (nmol/ml)b

1.74 (1.25–2.44)

0.001

IMA (ABSU)a

89.22 (0.004–1.87 × 106)

0.376

IMA (ABSU)b

1.51 × 103 (0.01–4.77 × 108)

0.257

  1. PACG primary angle-closure glaucoma, OR odds ratio, 95% CI 95% confidence interval, MDA malondialdehyde, AOPP advanced oxidation protein products, PC protein carbonyl, IMA ischemia modified albumin, ABSU absorbance units
  2. #Adjusted for sex and age
  3. aAll subjects (n=35 for control subjects, n=64 for PACG patients)
  4. bControl and PACG subjects after excluding subjects with DM, hypertension, CVD, and smoking (n= 26 for the control group and 36 for PACG patients)
  5. P < 0.013 was considered significant after the Bonferroni correction