Correlating SFTPC gene variants to interstitial lung disease in Egyptian children

Journal of Genetic Engineering and Biotechnology

Table 1 Summary of the clinical data of the patients

No.	Age	Sex	Consang.	Age of onset	Other affected member	Symptoms	Echo	Short stature/FTT	CT chest
P1	5 y	F	+ve	1 y	+ve	Cough-clubbing-dyspnea	−ve	++/−	Ground glass
P2	1.5 y	M	−ve	1 y	+ve	Cough-dyspnea	−ve	−/−	Ground glass
P3	7 y	M	+ve	1.5 y	+ve	Cough-cyanosis dyspnea-clubbing-OIH	PH	−/−	Ground glass
P4	8 y	M	+ve	2 y	−ve	Cough-dyspnea-clubbing	−ve	++/−	Ground glass
P5	19 y	F	+ve	4 y	−ve	Cough-dyspnea	PH	−/−	Mosaic
P6	10 y	F	−ve	1 y	−ve	Cough-dyspnea	PH	−/−	Ground glass
P7	6.5 y	M	−ve	2 y	−ve	Cough-dyspnea	PDA	−/++	Mosaic
P8	6 y	M	+ve	3 y	+ve	Cough-dyspnea-clubbing	PH	−/−	Ground glass
P9	11 y	F	−ve	2 y	+ve	Cough-dyspnea	−ve	−/−	Mosaic
P10	9 y	M	+ve	1.5 y	−ve	Cough-dyspnea-clubbing	PH	+/−	Ground glass
P11	11 y	F	+ve	2 y	+ve	Cough-dyspnea	PH-PFO	−/−	Ground glass
P12	8 y	F	−ve	1.5 y	+ve	Cough-dyspnea-clubbing	PH	−/−	Ground glass
P13	11 y	M	−ve	10 y	+ve	Cough-dyspnea-clubbing	−ve	−/−	Ground glass
P14	5 y	F	+ve	4 y	+ve	Cough-dyspnea-clubbing	−ve	−/−	Ground glass
P15	12 y	F	+ve	6 y	−ve	Cough-dyspnea-clubbing	+ve	++/−	Ground glass
P16	7 y	M	−ve	1 y	−ve	Cough-dyspnea-clubbing	−ve	−/−	Ground glass
P17	8 y	F	+ve	4 y	+ve	Cough-dyspnea	PH	−/−	Ground glass
P18	7 y	M	−ve	3 y	−ve	Cough-dyspnea	−ve	++/−	Ground glass
P19	10 y	M	+ve	5 y	+ve	Cough-dyspnea	PH	−/−	Ground glass
P20	8.5 y	M	−ve	2.5 y	−ve	Cough-dyspnea	−ve	−/−	Ground glass

PH pulmonary hypertension, PDA patent ductus arteriosus, PFO patent foramen oval, FTT failure to thrive