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Journal of Genetic Engineering and Biotechnology
Fig. 10 | Journal of Genetic Engineering and Biotechnology

Fig. 10

From: Osteogenic enhancement of modular ceramic nanocomposites impregnated with human dental pulp stem cells: an approach for bone repair and regenerative medicine

Fig. 10

Histopathological sections of rabbits transplanted by hDP-MSCs and ceramic nanocomposites scaffold. Sections of bone of A tested dental pulp stem cells (DP-MSCs) with ceramic nanocomposites (C1) after 4 weeks show nodules like shape of new formed bone and few vacuoles that are filled with connective tissue. B Control of ceramic nanocomposites (C1) only after 4 weeks shows many of vacuoles surrounded by new formed bone. C Tested dental pulp stem cells (DP-MSCs) with ceramic nanocomposites (C2). After 4 weeks, extensive regions of the mature bone showed in the defect parts. Note the collagen-filled vacuole. D Control of ceramic nanocomposites (C2) only after 4 weeks shows thickness of bone regeneration in the defect. Few vacuoles that are filled with connective tissues. E Tested dental pulp stem cells (DP-MSCs) with ceramic nanocomposites (C3) after 4 weeks show that the defect is filled with mature bone, and small vacuoles are present. F Control of ceramic nanocomposites (C3) after 4 weeks large vacuoles embedded in the new formed bone (H&E stain; scale bar: 20 μm)

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