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Table 3 Effect of different treatments on VEGF, NF-kB, and AFP in DEN-treated rats (aP < 0.05 compared to control; bP < 0.05 compared to DEN group)

From: Regulation of Sirtuin-3 and ERK1/2/p38MAPK by the combination Ga nanoparticles/γ-radiation low dosage: an effective approach for treatment of hepatocellular carcinoma

Parameter

G1

Control

G2

RAD

G3

GaNPs

G4

GaNPs + R

G5

DEN

G6

DEN + GaNPs

G7

DEN + RAD

G8

DEN + GaNPs + RAD

AFP

(ng/ml)

0.48 ± 0.04

0.6 ± 0.04b

0.5 ± 0.03b

0.3 ± 0.02ab

1.98 ± 0.1a

0.50 ± 0.09ab

0.75 ± 0.05ab

0.45 ± 0.03ab

NF-κB

(ng/ml)

69.1 ± 4.2

64.7 ± 5.3b

59.3 ± 4.7b

72.0 ± 6.1b

195.0 ± 14.6a

123.0 ± 11.8ab

141.0 ± 12.5ab

109.0± 10.3ab

VEGF

(pg/ml)

33.5 ± 1.7

30.2 ± 0.46b

31.9 ± 0.75b

36.8 ± 2.22b

110 ± 10.3a

55.1 ± 3.09ab

77.8 ± 6.4ab

41.7 ± 3.5ab