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Table 3 Prediction of evolutionary conservation by ConSurf

From: Determination of deleterious single-nucleotide polymorphisms of human LYZ C gene: an in silico study

SNP ID Amino acid change Prediction (Score) ConSurf Prediction Functional/structural
rs1800973 T88N 3 Variable -
rs121913547 I74T 8 Conserved -
rs121913549 F75I 9 Conserved s
rs387906535 D67H 6 Moderately conserved -
rs387906536 W82R 9 Conserved f
rs121913548 D85H 5 Moderately conserved -
rs147465274 R80C 4 Moderately conserved -
rs200491782 R116S 4 Moderately conserved -
  1. According to the ConSurf server, “f” — functional residue and “s” — structural residue