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Table 4 IC50 (μM), Km (μM), Vmax (μmol/min/mg protein), and type of inhibition for BaGST2 and BaGST3 using CDNB as a substrate. The type of inhibition was measured in the presence of less than I20 μM of inhibitor

From: Biochemical characterization and peptide mass fingerprinting of two glutathione transferases from Biomphalaria alexandrina snails (Gastropoda: Planorbidae)

Inhibitor used BaGST2 BaGST3
IC50 Km Vmax Type of inhibition IC50 Km Vmax Type of inhibition
Non - 0.85 75.5 - - 50.0 48.8 -
BSP 80.4 2.75 75.5 Competitive 95.0 450 48.8 Mixed
Hematin 1.35 2.54 13.7 Mixed 0.46 50.0 15.8 Noncompetitive
CB 2.35 3.85 75.5 Competitive 0.58 750 48.8 Competitive