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Fig. 4 | Journal of Genetic Engineering and Biotechnology

Fig. 4

From: Application of Baculovirus Expression Vector system (BEV) for COVID-19 diagnostics and therapeutics: a review

Fig. 4

The NSPs produced in BEV and their inhibitors. There is a total of five SAR-COV-2 Nsp proteins produced in BEV and tested with their respective inhibitors. Nsp3 was inhibited by Dihydro-tanshinone I. Nsp 10 is a cofactor for Nsp14. Nsp12, which encodes for RdRP, was inhibited by 10 drugs (Remdesivir, Favipiravir, Penciclovir, X3, Suramin, Cancidas, LTX-315, GSK-650394, and Suramin). Suramin inhibited both Nsp12 and Nsp13. Nsp14 was inhibited by Patulin and ATA

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