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Journal of Genetic Engineering and Biotechnology

Table 7 The MIC changes for Nigrocin-PN and ampicillin in different processed S. aureus strains

From: A novel antimicrobial peptide found in Pelophylax nigromaculatus

Different passage process groups

MIC (µM)

Nigrocin-PN

Ampicillin

Group A strain

16

0.5

Group B strain

16

4.0

Group C strain

16

0.5

Group D strain

32

1.0

  1. Group A strain: S. aureus was passaged under drug-free background
  2. Group B strain: S. aureus was passaged under ¼ MIC ampicillin stress
  3. Group C strain: S. aureus was passaged under ½ MIC Nigrocin-PN stress
  4. Group D strain: S. aureus was passaged under the combination of ½ MIC Nigrocin-PN and 1/8 MIC ampicillin
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