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Table 5 Anticancer activity of Nigrocin-PN and its derivates against several cancer cell lines

From: A novel antimicrobial peptide found in Pelophylax nigromaculatus

 

IC50 (µM)

Nigrocin-PN (µM)

Nigrocin-M1 (µM)

Nigrocin-M2 (µM)

H157

18.04

24.00

ND

PC-3

53.03

31.27

ND

U-251MG

73.65

25.06

ND

MCF-7

ND

24.60

ND

  1. ND, Not determined, IC50 was over 100 µM