In silico multi-epitope Bunyumwera virus vaccine to target virus nucleocapsid N protein

Journal of Genetic Engineering and Biotechnology

Table 2 MHC Class-I epitopes antigenicity, allergenicity, toxicity, and topology

Position	HLA class 1 alleles & supertypes	Peptide sequence	Antigenicity	Allergenicity	Toxicity	Topology
9	A_1,A_24,B₇,B₈,B₃₉,B₅₈,B₆₂	VAANTSSTF	Antigen 0.4577	Allergen	Non-toxic	Inside
15	A₁,A₃,A₂₆,B₈,B₂₇,B₃₉,B₅₈,B₆₂	STFDPEVAY	Antigen 0.7863	Allergen	Non-toxic	Outside
69	A₁,A₃,A₂₄,A₂₆,B₇,B₈,B₂₇,B₅₈,B₆₂	KVTVFNTNF	Antigen 0.5884	Non-allergen	Non-toxic	Inside
149	A₁,A₃,A₂₄,A₂₆,B₈,B₂₇,B₃₉,B₅₈,B₆₂	EMFLGTFKF	Non-antigen 0.0983	Non-allergen	Non-toxic	Outside
197	A₁,A₂,A₃,A₂₆,B₇,B₈,B₃₉,B₅₈,B₆₂	KVNEVQSAL	Non-antigen 0.3378	Allergen	Non-toxic	Inside
143	A₁,A₂₄,A₂₆,B₈,B₃₉,B₄₄,B₅₈,B₆₂	SFFPGSEMF	Non-antigen −0.0452	Non-allergen	Non-toxic	Outside
28	A₁,A₃,A₂₆,B₇,B₈,B₂₇,B₅₈,B₆₂	RIYTTGLSY	Antigen 0.4063	Allergen	Non-toxic	Inside
94	A₁,A₂,A₃,A₂₆,B₈,B₂₇,B₅₈,B₆₂	RLSGFLARY	Non-antigen 0.3265	Non-allergen	Non-toxic	Outside
221	A₁,A₂₆,B₇,B₈,B₂₇,B₅₈,B₆₂	AAREFLAKF	Non-antigen −1.2944	Allergen	Non-toxic	Inside
118	A_1,B_7,B₈,B_39,B_44,B₆₂	IKSKIINPL	Antigen 0.4284	Non-allergen	Non-toxic	Inside
55	A_1,B_8,B_27,B₃₉	KRSEWEVTL	Antigen 1.5287	Non-allergen	Non-toxic	Inside
57	A_1,A_2,B_7,B_8,B_27,B_39,B₄₄	SEWEVTLNL	Antigen 0.7108	Non-allergen	Non-toxic	Outside