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Table 5 Multinomial regression analysis for NAFLD in obese T2DM patients under dominant and recessive models (n = 76)

From: Sociodemographic and genetic determinants of nonalcoholic fatty liver disease in type 2 diabetes mellitus patients

  2 × 2 crosstabs Dominant model Recessive model
NAFLD and obese (BMI ≥ 30.0 Kg/m2) Non-NAFLD and nonobese (BMI < 30.0 Kg/m2) OR AOR 95.0% Cl for AOR p-value AOR 95.0% Cl for AOR p-value
n (%) n (%) Lower Upper Lower Upper
Age (years) ≤ 50 20 (46.5) 23 (53.5) 1.180 1.671 0.493 5.668 0.410 1.562 0.464 5.257 0.471
> 50 14 (42.4) 19 (57.6)
Sex Female 28 (58.3) 20 (41.7) 5.130 3.411 0.997 11.671 0.051 2.831 0.822 9.757 0.099
Male 06 (21.4) 22 (78.6)
Family income
(PKR/month)
≤ 20000 22 (44.9) 27 (55.1) 1.020 0.786 0.255 2.424 0.675 0.653 0.209 2.042 0.464
> 20000 12 (44.4) 15 (55.6)
Education Illiterate 19 (61.3) 12 (38.7) 3.170 2.626 0.818 8.429 0.105 3.323 1.010 10.937 0.048
Literate 15 (33.3) 30 (66.7)
Smoking Yes 0 (0.0) 02 (100.0) 0.000 3.123
E-008
0.000 .c 0.998 3.998
E-008
0.000 .c 0.998
No 34 (45.9) 40 (54.1)
Any comorbidity Yes 18 (51.4) 17 (48.6) 1.650 1.567 0.558 4.401 0.394 1.758 0.619 4.990 0.289
No 16 (39.0) 25 (61.0)
Family H/o diabetes Yes 26 (48.1) 28 (51.9) 1.630 1.257 0.375 4.205 0.711 1.482 0.451 4.869 0.517
No 08 (36.4) 14 (63.6)
Duration of diabetes > 10 years 08 (53.3) 07 (46.7) 1.540 1.614 0.378 6.885 0.518 1.205 0.276 5.267 0.804
≤ 10 years 26 (42.6) 35 (57.4)
HbA1c (%) > 8.0 22 (51.2) 21 (48.8) 1.830 2.153 0.758 6.113 0.150 2.061 0.729 5.827 0.173
≤ 8.0 12 (36.4) 21 (63.6)
PNPLA3 genotype GG + CG 19 (61.3) 12 (38.7) 3.170 3.270 1.131 9.455 0.029  
CC 15 (33.3) 30 (66.7)
PNPLA3 genotype GG 12 (70.6) 05 (29.4) 4.040   4.534 1.221 16.826 0.024
CG + CC 22 (37.3) 37 (62.7)
  1. n (%), row percent; NAFLD, nonalcoholic fatty liver disease; T2DM, type 2 diabetes mellitus; BMI, body mass index; OR, odds ratio; AOR, adjusted odds ratio; CI, confidence interval. p-value ≤ 0.05 considered statistically significant