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Table 4 Binary logistic regression for NAFLD in obese T2DM patients under dominant and recessive models (n = 129)

From: Sociodemographic and genetic determinants of nonalcoholic fatty liver disease in type 2 diabetes mellitus patients

  2 × 2 crosstabs Dominant model Recessive model
NAFLD and BMI (≥ 30.0 Kg/m2) OR AOR 95.0% Cl for AOR p-value AOR 95.0% Cl for AOR p-value
Yes
n (%)
No
n (%)
Lower Upper Lower Upper
Age (years) ≤ 50 20 (26.3) 56 (73.7) 0.995 1.749 0.496 6.166 0.385 1.923 0.538 6.872 0.314
> 50 14 (26.4) 39 (73.6)
Sex Female 28 (32.6) 58 (67.4) 2.977 4.010 1.156 13.912 0.029 3.208 0.934 11.015 0.064
Male 06 (14.0) 37 (86.0)
Family income
(PKR/month)
≤ 20000 22 (27.2) 59 (72.8) 1.119 0.807 0.244 2.675 0.726 0.806 0.245 2.647 0.722
> 20000 12 (25.0) 36 (75.0)
Education Illiterate 19 (38.8) 30 (61.2) 2.744 2.936 0.913 9.444 0.071 3.506 1.080 11.375 0.037
Literate 15 (18.8) 65 (81.3)
Smoking Yes 0 (0.0) 06 (100.0) 0.000 0.000 0.000  . 0.999 0.000 0.000  . 0.999
No 34 (27.6) 89 (72.4)
Any comorbidity Yes 18 (29.0) 44 (71.0) 1.304 1.616 0.530 4.924 0.399 1.779 0.572 5.536 0.320
No 16 (23.9) 51 (76.1)
Family H/o diabetes Yes 26 (28.0) 67 (72.0) 1.358 1.798 0.497 6.504 0.371 2.148 0.590 7.820 0.246
No 08 (22.2) 28 (77.8)
Duration of diabetes > 10 years 08 (29.6) 19 (70.4) 1.231 1.978 0.472 8.295 0.351 1.481 .341 6.434 0.600
≤ 10 years 26 (25.5) 76 (74.5)
HbA1c (%) > 8.0 22 (29.3) 53 (70.7) 1.453 1.838 0.604 5.592 0.283 1.856 0.607 5.672 0.278
≤ 8.0 12 (22.2) 42 (77.8)
PNPLA3 genotype GG + CG 19 (39.6) 29 (60.4) 2.883 3.303 1.099 9.920 0.033  
CC 15 (18.5) 66 (81.5)
PNPLA3 genotype GG 12 (44.4) 15 (55.6) 2.909   4.547 1.123 18.408 0.034
CG + CC 22 (21.6) 80 (78.4)
  1. n (%), row percent; NAFLD, nonalcoholic fatty liver disease; T2DM, type 2 diabetes mellitus; BMI, body mass index; OR, odds ratio; AOR, adjusted odds ratio; CI, confidence interval. p-value ≤ 0.05 considered statistically significant