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Table 3 Genotypes and alleles in the hypertensive compared to non-hypertensive patients

From: Edema in childhood nephrotic syndrome: possible genes–hormones interplay

 

Hypertensives (N=18)

N (%)

Non-hypertensives (N=82)

N (%)

P, OR (95% CI)

ANP (A2843G)

  

0.35

Genotypes:

  AA

12 (66.7%)

53 (64.6%)

 

  AG

6 (33.3%)

21 (25.6%)

 

  GG

0

8 (9.8%)

 

Alleles:

  A allele

30 (83.3%)

127 (77.4%)

0.44

  G allele

6 (16.7%)

37 (22.6%)

NPRC C (-55)

  

0.43

Genotypes:

  AA

0

7 (8.5%)

 

  AC

5 (27.8%)

21 (25.6%)

 

  CC

13 (72.2%)

54 (65.9%)

 

Alleles:

  A allele

5 (13.9%)

35 (21.3%)

0.3

  C allele

31 (86.1%)

129 (78.7%)

ScaI gene polymorphism

  

0.008

Genotypes:

  A1A1

1 (5.6%)

5 (6.1%)

0.9

  A1A2

0

30 (36.6%)

0.03

  A2A2

17 (94.4%)

47 (57.3%)

0.003,12.6 (1.6-99.7)

Alleles:

  A1 allele

2 (5.6%)

40 (24.4%)

0.012, 0.18 (0.04-0.79)

  A2 allele

34 (94.4%)

124 (75.6%)

  1. ANP atrial natriuretic peptide, NPRC natriuretic peptide receptor clearance, OR odds ratio, CI confidence interval
  2. Bold values are the statistically significant values