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Table 2 Quality parameters of the structured MeCP2 model using Swiss PDB Viewer 4.1.0 program

From: Variable predicted pathogenic mechanisms for novel MECP2 variants in RTT patients

Quality parameters D121 R133 S359 P403
Residues with conformational angles lie outside allowed regions - - - +
Residues deviating from Trans peptide bonds - - + +
Residues with protein problems - - Buried side chaina -
Residues according to its threading energy Within normal range Within normal range Within normal range Within normal range
  1. (-) means score lies in allowed range, but (+) means score lies out allowed range
  2. aResidues that could make H bonds but do not