Table 2 Quality parameters of the structured MeCP2 model using Swiss PDB Viewer 4.1.0 program
From: Variable predicted pathogenic mechanisms for novel MECP2 variants in RTT patients
Quality parameters | D121 | R133 | S359 | P403 |
|---|---|---|---|---|
Residues with conformational angles lie outside allowed regions | - | - | - | + |
Residues deviating from Trans peptide bonds | - | - | + | + |
Residues with protein problems | - | - | Buried side chaina | - |
Residues according to its threading energy | Within normal range | Within normal range | Within normal range | Within normal range |