Fig. 5From: Dynamic disequilibrium-based pathogenicity model in mutated pyrin’s B30.2 domain—Casp1/p20 complexRemodeling of ASC-independent NF-kB activation pathway (modified predictive model) according to our molecular mechanics scores of mutant B30.2/SPRY domain. The three upright lines between casp-1/p20 and B30.2/SPRY mean high binding affinity, while the upright arrows mean elevated quantity, and the bold truncated line means inhibitory effectBack to article page