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Table 2 Comparison between laboratory characteristics of individuals included in this work based on METAVIR fibrosis stages (n = 249)

From: Prevalence of Helicobacter pylori infection in patients with chronic hepatitis C

Variablesa Group I (n = 95), no fibrosis Group II (n = 90), fibrosis Group III (n = 64), cirrhosis Tukey’s post hoc test
Group I vs. II Group I vs. III Group II vs. III
Age (year) 32.26 ± 0.65 43.32 ± 1.21 54.00 ± 2.08 < 0.0001* < 0.0001* < 0.0001*
ALT (U/L) 22.36 ± 0.92 54.07 ± 2.45 67.87 ± 3.59 < 0.0001* < 0.0001* < 0.0001*
AST (U/L) 24.09 ± 1.23 56.87 ± 3.39 68.97 ± 4.35 < 0.0001* < 0.0001* 0.014*
Total bilirubin (mg/dl) 0.71 ± 0.03 1.79 ± 0.30 1.78 ± 0.18 < 0.0001* < 0.0001* 1.00
Albumin (g/L) 3.88 ± 0.07 3.48 ± 0.17 2.97 ± 0.11 0.030* < 0.0001* 0.030*
Platelets (109/L) 240.06 ± 5.43 172.03 ± 22.24 130.67 ± 21.77 0.015* < 0.0001* 0.259
AFP (U/L) 1.35 ± 0.06 37.54 ± 6.98 94.18 ± 23.95 0.001* < 0.0001* < 0.0001*
  1. Variables were expressed as mean ± SEM
  2. aReference values: alanine aminotransferase (ALT) (male up to 41 U/L, female up to 31 U/L); aspartate aminotransferase (AST) (male up to 37 U/L, female up to 31 U/L); total bilirubin up to 1 mg/dL; albumin 3.8‑5.4 g/dL; platelet count 150‑400 × 109/L; alpha fetoprotein (AFP) up to 10 U/L
  3. *P < 0.05 is considered significant