Table 3 Determination of succinate dehydrogenase (SDH) and coenzyme Q reductase (complex II) activities by IC50 in normal fibroblast cell lines
Relative enzyme activity % | Negative control (untreated cells) | Chrysin Mean± SEM *p-value | CCNPs Mean± SEM *p value | 5-Fluorouracil Mean± SEM *p value |
|---|---|---|---|---|
Succinate dehydrogenase by MTT test | 100 ± 0 | 80.90 ±0.003 P <0.0001 | 89.06 ±0.0003 P <0.0001 | 90± 0.003 P <0.0001 |
Ubiquinone reductase by DCPI dye | 100 ± 0 | 90±0.002 P <0.0001 | 85±0.02 P <0.0001 | 95 ±0.001 P < 0.0001 |