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Table 3 Determination of succinate dehydrogenase (SDH) and coenzyme Q reductase (complex II) activities by IC50 in normal fibroblast cell lines

From: Study of the inhibitory effects of chrysin and its nanoparticles on mitochondrial complex II subunit activities in normal mouse liver and human fibroblasts

Relative enzyme activity % Negative control (untreated cells) Chrysin
Mean± SEM
*p-value
CCNPs
Mean± SEM
*p value
5-Fluorouracil
Mean± SEM
*p value
Succinate dehydrogenase by MTT test 100 ± 0 80.90 ±0.003
P <0.0001
89.06 ±0.0003
P <0.0001
90± 0.003
P <0.0001
Ubiquinone reductase by DCPI dye 100 ± 0 90±0.002
P <0.0001
85±0.02
P <0.0001
95 ±0.001
P < 0.0001
  1. *p value versus the negative control (untreated cells)