Table 3 Determination of succinate dehydrogenase (SDH) and coenzyme Q reductase (complex II) activities by IC50 in normal fibroblast cell lines
| Relative enzyme activity % | Negative control (untreated cells) |
Chrysin Mean± SEM *p-value |
CCNPs Mean± SEM *p value |
5-Fluorouracil Mean± SEM *p value |
|---|---|---|---|---|
| Succinate dehydrogenase by MTT test | 100 ± 0 |
80.90 ±0.003 P <0.0001 |
89.06 ±0.0003 P <0.0001 |
90± 0.003 P <0.0001 |
| Ubiquinone reductase by DCPI dye | 100 ± 0 |
90±0.002 P <0.0001 |
85±0.02 P <0.0001 |
95 ±0.001 P < 0.0001 |