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Table 4 BCL9 CN gain according to male gender and clinical and HCC characteristics parameters

From: The role of BCL9 genetic variation as a biomarker for hepatitis C-related hepatocellular carcinoma in Egyptian patients

Parameters

Total male patients, N = 39

CNV in male patients

P-value

Gain, N = 7

No gain, N = 32

Age (mean ± SD), years

62.64 ± 8.34

64.00 ± 5.69

62.34 ± 8.86

0.761

BMI (mean ± SD), kg/m2

25.0 ± 3.10

23.57 ± 3.02

25.32 ± 3.08

0.212

Hb (mean ± SD), g/dl

12.73 ± 1.97

12.90 ± 2.04

12.69 ± 1.99

0.707

TLC (mean ± SD), 103/mm3

5.60 ± 2.52

5.08 ± 1.75

5.72 ± 2.67

0.654

PLT (mean ± SD), 103/mm3

141.82 ± 69.38

143.71 ± 64.76

141.41 ± 71.33

0.629

AST (mean ± SD), U/l

55.15 ± 33.77

66.86 ± 42.98

52.59 ± 31.67

0.484

ALT (mean ± SD), U/l

49.26 ± 35.31

55.0 ± 26.64

48.00 ± 37.1

0.287

Bil.T (mean ± SD), mg/dl

1.15 ± 0.52

1.07 ± 0.50

1.17 ± 0.53

0.603

AFP, no. (%)

< 4.5

5 (12.82%)

1 (14.29%)

4 (12.50%)

1.000

≥ 4.5

34 (87.18%)

6 (85.71%)

28 (87.5%)

BCLC

0

6 (15.38%)

1 (14.29%)

5 (15.6%)

0.929

A

9 (23.08%)

2 (28.57%)

7 (21.87%)

0.653

C

20 (51.28%)

4 (57.14%)

16 (50.0%)

0.732

D

4 (10.26%)

0 (0.0%)

4 (12.5%)

0.323

F.H of HCC

Yes

6 (15.38%)

1 (14.29%)

5 (15.63%)

1.00

No

33 (84.62%)

6 (85.71%)

27 (84.37%)

Performance status

0

22 (56.41%)

3 (42.86%)

19 (59.38%)

0.426

< 1

1 (2.56%)

0 (0.0%)

1 (3.12%)

0.636

> 1

16 (41.03%)

4 (57.14%)

12 (37.5%)

0.339

Liver size

Average

18 (46.15%)

4 (57.14%)

14 (43.75%)

0.520

Enlarged

18 (46.15%)

3 (42.86%)

15 (46.88%)

0.847

Shrunken

3 (7.70%)

0 (0.0%)

3 (9.37%)

0.399

Child score

A

26 (66.67%)

4 (57.14%)

22 (68.75%)

0.666

B

13 (33.33%)

3 (42.86%)

10 (31.25%)

Child grade

6.08 ± 1.13

6.0 ± 1.0

6.09 ± 1.17

0.957

No. of focal lesions

Single

23 (58.97%)

5 (71.43%)

18 (56.25%)

1.00

Multiple

16 (41.03%)

2 (28.57%)

14 (43.75%)

Focal lesion size

4.83 ± 3.46

5.86 ± 4.85

4.60 ± 3.14

0.707

P.V.

Patent

7 (17.95%)

2 (28.57%)

5 (15.63%)

0.588

Thrombosed

32 (82.05%)

5 (71.43%)

27 (84.37%)

Ascites

Yes

9 (23.08%)

2 (28.57%)

7 (21.87%)

0.653

No

30 (76.92%)

5 (71.43%)

25 (78.13%)

  1. The data were analyzed by the non-parametric Kruskal-Wallis and chi-square tests.
  2. *P-value ≤ 0.05 significant
  3. **P-value ≤ 0.01 highly significant