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Table 2 The antagonistic effect of P. columbinus extract in alleviating the toxic effect of CTX on serum hormone levels in the experimental rats

From: Assessment role of total phenols and flavonoids extracted from Pleurotus columbinus mushroom on the premature ovarian failure induced by chemotherapy in rats

Groups

E2 (pg/ml)

AMH (ng/ml/)

FSH (mIU/ml)

LH (mIU/ml)

Control

11.05 ± 0.78a

7.10 ± 0.50a

4.17 ± 0.07bc

1.30 ± 0.02a

CTX

4.51 ± 0.33b

2.56 ± 0.04b

6.65 ± 0.18a

0.56 ± 0.01c

TP

12.13 ± 1.35a

7.16 ± 0.62a

3.93 ± 0.06c

1.27 ± 0.007ab

CTX+ TP

12.30 ± 1.58a

6.30 ± 0.41a

4.75 ± 0.31b

1.14 ± 0.02b

  1. Each value represents mean ± SE (n = 8). a, b, ab, and c denote significant difference from normal-control, CTX induced POF, P. columbines extract control and POF+P. columbinus (before and after) groups, respectively, p < 0.05 (one-way ANOVA followed by post hoc Tukey)