| |
GDM N = 114 (%)
|
Controls N = 114 (%)
|
P value; OR (95th CI)
|
|---|
|
rs7903146 (C/T)
|
|
CC
|
18 (15.2%)
|
41 (35%)
|
Ref
|
|
CT
|
53 (46.5%)
|
62 (54%)
|
0.04; 1.9 (1.0 to 3.78)
|
|
TT
|
43 (37.7%)
|
11 (9.6%)
|
<0.001; 8.9 (3.7–21.1)
|
|
CT+TT vs. CC
|
96 (84.2%)
|
73 (64%)
|
<0.001; 3 (1.5–5.6)
|
|
TT vs. CC +CT
|
43 (47.7%)
|
11 (9.6%)
|
<0.001; 5.6 (2.7–11.7)
|
|
HWE
|
0.8
|
0.07
| |
|
rs7903146 (C/T)
|
|
C
|
39%
|
63.1%
|
Ref
|
|
T
|
61%
|
36.8%
|
<0.001; 2.6 (1.8–3.9)
|
|
rs12255372 (G/T)
|
|
GG
|
31 (27.2%)
|
60 (52.6%)
|
Ref
|
|
GT
|
55 (48.2 %)
|
45 (39.5%)
|
0.004; 2.3 (1.3–4.2 )
|
|
TT
|
28 (24.6%)
|
9 (7.9%)
|
<0.001; 6 (2.5–14.3)
|
|
GT+TT vs. GG
|
83 (72.8%)
|
54 (47.7%)
|
<0.001; 2.9 (1.7–5.1)
|
|
TT vs. GG +GT
|
28 (24.6%)
|
9 (9.7%)
|
0.001; 3.7 (1.7–8.4 )
|
|
HWE
|
0.7
|
0.8
| |
|
rs12255372 (G/T)
|
|
G
|
48.7%
|
24.3%
|
Ref
|
|
T
|
51.3%
|
75.5%
|
<0.001; 2.9 (1.9–4.4 )
|
- OR odds ratio, CI confidence interval, HWE Hardy–Weinberg equation
- P<0.05 is considered significant
