Table 2 Diagnostic power of single and combined candidate markers (CRP, cholesterol, BMI, ALT, and miRNA34) to diagnose NAFLD

miRNA-34

0.72 (0.66–0.77)

< 0.0001

3.5

70

64

81

49

ALT

0.73 (0.67–0.79)

< 0.0001

32

77

66

83

57

BMI

0.81 (0.76–0.86)

< 0.0001

25

75

67

83

56

Cholesterol

0.85 (0.79–0.90)

< 0.0001

160

83

83

92

67

CRP

0.88 (0.84–0.92)

< 0.0001

3

85

85

92

72

CRP+ cholesterol

0.93 (0.89–0.96)

< 0.0001

1.6

90

85

93

79

CRP+ cholesterol+ BMI

0.94 (0.91–0.97)

< 0.0001

1.4

91

87

95

78

CRP+ cholesterol+ BMI+ALT

0.95 (0.93–0.97)

< 0.0001

1.4

92

88

95

81

CRP+ cholesterol+ BMI+ALT+ miRNA-34

0.98 (0.93–0.99)

< 0.0001

1.5

93

90

95

86