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Table 4 Predicted consensus GO terms for YDR models

From: Role of “dual-personality” fragments in HEV adaptation—analysis of Y-domain region

Consensus GO terms

Description

HEV

 GO:0020037~heme binding

Interacting selectively and non-covalently with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring

 GO:0009055~electron transfer activity

Any molecular entity that serves as an electron acceptor and electron donor in an electron transport chain

 GO:0004129~cytochrome-c oxidase activity

Catalysis of the reaction: 4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O

Human

 GO:0030598~rRNA N-glycosylase activity

Catalysis of the hydrolysis of the N-glycosylic bond at A-4324 in 28S rRNA from rat ribosomes or corresponding sites in 28S RNA from other species

Swine

 GO:0009486~cytochrome bo3 ubiquinol oxidase activity

Catalysis of the reaction: 2 ubiquinol + O2 + 4 H+ = 2 ubiquinone + 2 H2O + 4 H+ [periplasmic space]

 GO:0020037~heme binding

Interacting selectively and non-covalently with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring

 GO:0005507~copper ion binding

Interacting selectively and non-covalently with copper (Cu) ions

 GO:0048039~ubiquinone binding

Interacting selectively and non-covalently with ubiquinone, a quinone derivative with a tail of isoprene units

 GO:0000166~nucleotide binding

Interacting selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose

 GO:0016682~oxidoreductase activity

Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces oxygen

 GO:0015453~-driven active transmembrane transporter activity

Primary active transport of a solute across a membrane, driven by the exothermic flow of electrons from a reduced substrate to an oxidized substrate

 GO:0009055~electron transfer activity

Any molecular entity that serves as an electron acceptor and electron donor in an electron transport chain

 GO:0015078~proton transmembrane transporter activity

Enables the transfer of a proton from one side of a membrane to the other

 GO:0018662~phenol 2-monooxygenase activity

Catalysis of the reaction: phenol + NADPH + H+ + O2 = catechol + NADP+ + H2O

Wild boar

 GO:0004096~catalase activity

Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O.

 GO:0020037~heme binding

Interacting selectively and non-covalently with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring

 GO:0016874~ligase activity

Catalysis of the joining of two molecules, or two groups within a single molecule, using the energy from the hydrolysis of ATP, a similar triphosphate, or a pH gradient

 GO:0050242~pyruvate, phosphate dikinase activity

Catalysis of the reaction: ATP + phosphate + pyruvate = AMP + diphosphate + 2 H(+) + phosphoenolpyruvate

 GO:0005524~ATP binding

Interacting selectively and non-covalently with ATP, adenosine 5′-triphosphate, a universally important coenzyme and enzyme regulator

 GO:0016301~kinase activity

Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule

 GO:0004108~citrate (Si)-synthase activity

Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA, where the acetyl group is added to the si-face of oxaloacetate; acetyl-CoA thus provides the two carbon atoms of the pro-S carboxymethyl group

Camel

 GO:0043167~ion binding

Interacting selectively and non-covalently with ions, charged atoms, or groups of atoms