Analysing the impact of the two most common SARS-CoV-2 nucleocapsid protein variants on interactions with membrane protein in silico

Journal of Genetic Engineering and Biotechnology

Table 1 Residues involved in hydrogen bonds and salt bridges between the mutant N protein and the M protein

Bond type	M protein atom	M protein residue	M protein residue position	N protein atom	N protein residue	N protein residue position	Distance
Hydrogen bond	N	ALA	2	OE2	GLU	323	3.04
Hydrogen bond	ND2	ASN	41	O	ARG	319	3.01
Hydrogen bond	NE	ARG	42	O	GLN	283	2.9
Hydrogen bond	NH1	ARG	42	O	ILE	320	2.71
Hydrogen bond	NH2	ARG	42	O	PHE	286	2.81
Hydrogen bond	NH2	ARG	42	O	GLY	287	2.66
Hydrogen bond	NH2	ARG	42	OD1	ASP	288	2.91
Hydrogen bond	NH2	ARG	44	OG	SER	312	2.77
Hydrogen bond	N	ILE	144	O	GLY	284	2.8
Hydrogen bond	N	ARG	146	OD1	ASP	288	3.19
Hydrogen bond	NH1	ARG	146	OE1	GLU	323	2.76
Hydrogen bond	N	GLY	147	OE1	GLU	290	2.84
Hydrogen bond	NH1	ARG	150	OE2	GLU	323	2.79
Hydrogen bond	NH2	ARG	150	OE1	GLU	323	2.73
Salt bridge	NH1	ARG	42	OD1	ASP	288	2.75
Salt bridge	NH1	ARG	146	OE2	GLU	323	2.76
Salt bridge	NH2	ARG	150	OE2	GLU	323	2.73