TLR4 gene polymorphisms in Egyptian vitiligo patients: insights into emerging association with clinical activity, family history, and response to therapy

Journal of Genetic Engineering and Biotechnology

Table 9 The distribution of TLR4 haplotypes in patients and controls

Haplotype	Frequency	Case, Control Ratio counts	Case-control frequencies	Chi-square	p value
ATT	0.229	51.0 : 149.0, 40.7 : 159.3	0.255, 0.203	1.507	0.2197
ACT	0.213	40.6 : 159.4, 44.7 : 155.3	0.203, 0.224	0.256	0.6126
GCT	0.208	36.0 : 164.0, 47.1 : 152.9	0.180, 0.236	1.874	0.171
GTT	0.147	31.4 : 168.6, 27.5 : 172.5	0.157, 0.137	0.309	0.5781
ACC	0.068	13.9 : 186.1, 13.4 : 186.6	0.069, 0.067	0.0060	0.9359
GTC	0.057	14.0 : 186.0, 8.7 : 191.3	0.070, 0.043	1.321	0.2504
GCC	0.043	8.6 : 191.4, 8.7 : 191.3	0.043, 0.043	0.0010	0.9712
ATC	0.034	4.6 : 195.4, 9.2 : 190.8	0.023, 0.046	1.573	0.2098

Variation in TLR4 SNPs haplotype frequencies in both patients and controls. No statistically significant difference of haplotypes frequencies between both groups was reported (p < 0.05)