Table 3 Distribution of TLR4 alleles and genotypes Vitiligo patients and healthy controls (group 1: below 18 years)
TLR4 polymorphisms | Case (N—24) N (%) | Control (N = 19) N (%) | OR (95% CI) | p/pc |
|---|---|---|---|---|
rs1927914 (C/T) | ||||
CC | 3 (12.5) | 0 (00.0) | 1.91 (1.41–2.56) | 0.24/NS |
CT | 3 (12.5) | 4 (21.1) | 0.54 (0.10–2.75) | 0.68/NS |
TT | 18 (75.0) | 15 (78.9) | 1.25 (0.29–5.27) | 0.76/NS |
C | 9 (18.7) | 4 (10.5) | 1.96 (0.55–6.95) | 0.37/NS |
T | 39 (81.3) | 34 (89.5) | 0.51 (0.14–1.81) | 0.37/NS |
rs1927911 (C/T) | ||||
CC | 4 (16.7) | 2 (10.5) | 1.70 (0.28–10.4) | 0.68/NS |
CT | 15 (62.5) | 16 (84.5) | 0.31 (0.07–1.38) | 0.12/NS |
TT | 5 (20.8) | 1 (5.30) | 0.21 (0.02–1.99) | 0.21/NS |
C | 23 (48.0) | 20 (52.6) | 0.82 (0.35–1.94) | 0.66/NS |
T | 25 (52.0) | 18 (47.4) | 1.21 (0.52–2.83) | 0.66/NS |
rs11536858 (A/G) | ||||
AA | 5 (20.8) | 5 (26.3) | 0.74 (0.18–3.05) | 0.67/NS |
AG | 17 (70.8) | 9 (47.4) | 2.69 (0.77–9.51) | 0.12/NS |
GG | 2 (8.30) | 5 (26.3) | 0.93 (0.39–2.21) | 0.21/NS |
A | 27 (54.6) | 19 (50.0) | 1.29 (0.54–3.02) | 0.56/NS |
G | 21 (45.4) | 19 (50.0) | 0.78 (0.33–1.83) | 0.56/NS |