Journal of Genetic Engineering and Biotechnology

Table 10 Relation of TLR4 haplotypes versus demographic, clinical, and outcome data in vitiligo patients

From: TLR4 gene polymorphisms in Egyptian vitiligo patients: insights into emerging association with clinical activity, family history, and response to therapy

		Haplotype
		ACC	ACT	ATC	ATT	GCC	GCT	GTC	GTT
Sex	M/F	0.04/0.09	0.26/0.14	0.04/0.00	0.26/0.25	0.00/0.07	0.17/0.18	0.06/0.07	0.13/0.18
Sex	P	0.45	0.14	0.20	0.89	0.12	0.96	1.00	0.96
Course	R/P	0.00/0.07	0.50/0.14	0.00/0.02	0.50/0.25	0.00/0.04	0.00/0.20	0.00/0.07	0.00/0.17
Course	P	1.00	0.05	1.00	0.34	1.00	0.59	1.00	0.58
Psychic trauma	NO/Yes	0.06/0.07	0.20/0.19	0.01/0.03	0.23/0.34	0.04/0.03	0.21/0.07	0.04/0.15	0.18/0.07
Psychic trauma	p	1.00	0.91	0.45	0.25	1.00	0.14	0.07	0.23
Alopecia	NO/Yes	0.05/0.14	0.19/0.21	0.02/0.00	0.26/0.21	0.04/0.00	0.18/0.14	0.04/0.21	0.17/0.07
Alopecia	p	0.25	1.00	1.00	1.00	1.00	1.00	0.06	0.46
FH vitiligo	NO/Yes	0.05/0.25	0.19/0.25	0.02/0.00	0.26/0.25	0.04/0.00	0.18/0.12	0.06/0.12	0.17/0.00
FH vitiligo	p	0.09	0.65	1.00	1.00	1.00	1.00	0.45	0.35
FHAIDs	NO/Yes	0.04/0.33	0.19/0.22	0.02/0.00	0.28/0.00	0.04/0.00	0.19/0.00	0.06/0.11	0.14/0.33
FHAIDs	p	0.02	1.00	1.00	0.11	1.00	0.35	0.49	0.15
Remission	NO/Yes	0.08/0.06	0.18/0.21	0.00/0.03	0.40/0.17	0.02/0.04	0.16/0.19	0.02/0.09	0.11/0.19
Remission	p	0.71	1.00	0.53	0.02	1.00	0.79	0.25	0.39
Type	Seg/Non-Seg	0.05/0.07	0.17/0.20	0.00/0.02	0.41/0.22	0.05/0.03	0.11/0.19	0.05/0.07	0.11/0.16
Type	p	1.00	1.00	1.00	0.12	0.53	0.73	1.00	0.73

M/F male/female, R/P regressive/progressive, Seg/Nonseg segmental/nonsegmental, FH family history, FHAIDs family history of auto-immune diseases, p value significant if < 0.05
Fischer exact test
Significant p value between ACC haplotype and family history of AID and between ATT haplotype and remission

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