Table 6 Helper T-lymphocyte epitopes predicted from the three hypothetical proteins of Plasmodium falciparum
Protein | HTL peptide | Position | NN-align P. rank | Antigenicity | IL10pred | IL4pred | IFNepitope |
|---|---|---|---|---|---|---|---|
XP_001350955.1 | LSDYTNIGSSLNPDD | 29–43 | 3.5 | 1.3058 | Non-inducer | Non-inducer | Negative |
|  | SDYTNIGSSLNPDDI | 30–44 | 3.7 | 1.0481 | Non-inducer | Inducer | Negative |
|  | DLSDYTNIGSSLNPD | 28–42 | 4.1 | 1.2586 | Non-inducer | Non-inducer | Negative |
XP_001351030.1 | NEAKMDSFIYQIYMM | 91–105 | 2.8 | 1.3318 | Inducer | Inducer | Positive |
|  | EAKMDSFIYQIYMMK | 92–106 | 1.9 | 1.4314 | Inducer | Inducer | Positive |
|  | AKMDSFIYQIYMMKS | 93–107 | 1.8 | 1.0428 | Inducer | Inducer | Positive |
|  | KMDSFIYQIYMMKSE | 94–108 | 1.7 | 1.0074 | Inducer | Inducer | Positive |
|  | MDSFIYQIYMMKSEF | 95–109 | 1.5 | 1.0892 | Inducer | Inducer | Positive |
|  | EYNEAKMDSFIYQIY | 89–103 | 3.4 | 1.1536 | Inducer | Inducer | Negative |
|  | YNEAKMDSFIYQIYM | 90–104 | 3.3 | 1.3256 | Inducer | Inducer | Negative |
|  | DSFIYQIYMMKSEFD | 96–110 | 0.46 | 0.7763 | Non-inducer | Inducer | Positive |
|  | SFIYQIYMMKSEFDK | 97–111 | 0.18 | 0.6950 | Non-inducer | Inducer | Positive |
|  | FIYQIYMMKSEFDKN | 98–112 | 0.18 | 1.0801 | Non-inducer | Inducer | Positive |
|  | IYQIYMMKSEFDKNL | 99–113 | 0.33 | 0.7683 | Non-inducer | Inducer | Positive |
|  | YQIYMMKSEFDKNLN | 100–114 | 0.63 | 0.9757 | Inducer | Inducer | Negative |
XP_001351047.1 | KYLKCFNNWYKNNFL | 29–43 | 4.9 | 0.6516 | Non-inducer | Inducer | Negative |