Journal of Genetic Engineering and Biotechnology

Table 7 Lipid profile and oxLDL response to atorvastatin treatment (40 mg/day) according to apolipoprotein B (ApoB) rs676210 polymorphism in the patients with CAD

From: ApoB gene polymorphism (rs676210) and its pharmacogenetics impact on atorvastatin response among Iraqi population with coronary artery disease

Parameters	Genotype (mean+SD)
Parameters	G/G (n = 18)	G/A (n = 21)	A/A (n = 9)	P value^‡
TC (mg/dl)	404.33±183.85	339.96±73.24	298.11±54.68	0.14
TG (mg/dl)	194.22±97.28	177.37±51.28	154.55±25.19	0.41
HDL (mg/dl)	48.22±5.09	48.60±5.70	51.11±5.48	0.46
LDL (mg/dl)	325.62±84.21	261.88±63.04	219.37±54.27^b	0.008
VLDL (mg/dl)	38.84±19.45	35.47±10.25	30.91±5.03	0.41
oxLDL (U/L)	71.25± 17.80	63.24± 20.95	58.13±18.29	0.25

^‡ANOVA significance test (2-tailed)
^bP ˂ 0.05 GG group vs. AA group

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