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Table 7 Lipid profile and oxLDL response to atorvastatin treatment (40 mg/day) according to apolipoprotein B (ApoB) rs676210 polymorphism in the patients with CAD

From: ApoB gene polymorphism (rs676210) and its pharmacogenetics impact on atorvastatin response among Iraqi population with coronary artery disease

Parameters Genotype (mean+SD)
G/G (n = 18) G/A (n = 21) A/A (n = 9) P value
TC (mg/dl) 404.33±183.85 339.96±73.24 298.11±54.68 0.14
TG (mg/dl) 194.22±97.28 177.37±51.28 154.55±25.19 0.41
HDL (mg/dl) 48.22±5.09 48.60±5.70 51.11±5.48 0.46
LDL (mg/dl) 325.62±84.21 261.88±63.04 219.37±54.27b 0.008
VLDL (mg/dl) 38.84±19.45 35.47±10.25 30.91±5.03 0.41
oxLDL (U/L) 71.25± 17.80 63.24± 20.95 58.13±18.29 0.25
  1. ANOVA significance test (2-tailed)
  2. bP ˂ 0.05 GG group vs. AA group