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Table 6 Lipid profile and oxLDL response to atorvastatin treatment (20 mg/day) according to apolipoprotein B (ApoB) rs676210 polymorphism in the patients with CAD

From: ApoB gene polymorphism (rs676210) and its pharmacogenetics impact on atorvastatin response among Iraqi population with coronary artery disease

Parameters

Genotype (mean+SD)

G/G (n = 24)

G/A (n = 13)

A/A (n = 15)

P value

TC (mg/dl)

270.71±78.63

294.11±52.64

273.81±78.97

0.76

TG (mg/dl)

151.14±41.61

145.00±31.37

156.36±45.49

0.83

HDL (mg/dl)

50.71±3.40

48.22±1.78

46.63±2.76b

0.01

LDL (mg/dl)

195.81±72.95

216.88±47.06

208.78±66.65

0.80

VLDL (mg/dl)

30.22±8.32

29.00±6.27

31.27±9.09

0.82

oxLDL (U/L)

82.90±29.01

78.72±18.24

77.58±26.16

0.90

  1. ANOVA significance test (2-tailed)
  2. bP ˂ 0.05 GG group vs. AA group