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Table 2 Chronic anti-inflammatory activity of Crateva adansonii leaf extracts and its Lupeol containing LF in male Wister albino rat

From: Analgesic and anti-inflammatory potential of Lupeol isolated from Indian traditional medicinal plant Crateva adansonii screened through in vivo and in silico approaches

Groups Drug treatment Wet qWEIGHT (mg) Dry weight (mg) Transudative weight (mg) Percentage inhibition
I Control 0.1%CMC 214.66 ± 8.36 58.62±1.69 156.04
II Indomethacin (20 mg/kg) 159.44 ± 5.32* 42.69 ± 2.27* 116.75** 25.18
III ME 200 mg/kg 186.67 ± 7.38 47.55 ± 1.97 139.12 10.84
IV ME 400 mg/kg 167.26 ± 6.34* 41.33 ± 2.26* 125.93* 19.29
V CE 200 mg/kg 180.62 ± 3.77 46.30 ± 3.15 134.32 13.92
VI CE 400 mg/kg 162.47 ± 6.37* 41.66 ± 1.96* 120.81* 22.58
VII LF 100 mg/kg 155.36 ± 5.75* 52.31 ± 2.55* 103.05** 33.96
  1. The data are presented as mean ± SEM n = 6. *p < 0.05, **p < 0.01 vs. control. Data were analyzed by using one-way ANOVA followed by Dunnett’s “t” test using the software Graph Pad
  2. ME Methanolic extract of C. adansonii leaf, CE Chloroform extract of C. adansonii leaf, LF Lupeol fraction