Table 2 Final HLA-II epitopes for vaccine construction
Epitope | Allele | Antigenicity | Allergenicity | Toxicity |
|---|---|---|---|---|
SNQIIKTAKASTNDN | HLA-DRB1*08:02 | Antigen (0.4273) | Non-allergen | Non-toxic |
SNQIIKTAKASTNDN | HLA-DRB1*11:01 | Antigen (0.4582) | Non-allergen | Non-toxic |
QIHGLYRSSDKTGGY | HLA-DRB1*11:01 | Antigen (0.7278) | Non-allergen | Non-toxic |
SNQIIKTAKASTNDN | HLA-DRB1*13:02 | Antigen (0.4582) | Non-allergen | Non-toxic |
MNDGSTYQSDLSKKF | HLA-DRB3 *01:01 | Antigen (0.8123) | Non-allergen | Non-toxic |
NDGSTYQSDLSKKFE | HLA-DRB3 *01:01 | Antigen (1.0840) | Non-allergen | Non-toxic |
STYQSDLSKKFEYNT | HLA-DRB3 *01:01 | Antigen (0.7472) | Non-allergen | Non-toxic |
TYQSDLSKKFEYNTE | HLA-DRB3 *01:01 | Antigen (0.8673) | Non-allergen | Non-toxic |
SKKFEYNTEKPPINI | HLA-DRB3*02:02 | Antigen (0.9356) | Non-allergen | Non-toxic |
KKFEYNTEKPPINID | HLA-DRB3*02:02 | Antigen (1.0198) | Non-allergen | Non-toxic |
KFEYNTEKPPINIDE | HLA-DRB3*02:02 | Antigen (1.0332) | Non-allergen | Non-toxic |
LGSMRIKNTDGSISL | HLA-DRB4*01:01 | Antigen (1.2178) | Non-allergen | Non-toxic |
DKKQLAISTLDFEIR | HLA-DRB4*01:01 | Antigen (1.4067) | Non-allergen | Non-toxic |
SNQIIKTAKASTNDN | HLA-DQA1*05:01/DQB1*03:01 | Antigen (0.4582) | Non-allergen | Non-toxic |
QIIKTAKASTNDNIK | HLA-DQA1*05:01/DQB1*03:01 | Antigen (0.5176) | Non-allergen | Non-toxic |